DETAILED NOTES ON B220

etravirine will reduce the extent or impact of abemaciclib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of abemaciclib with strong CYP3A4 inducers lessens plasma focus of abemaciclib and its metabolites.Dato-Dxd did not create significant toxicity at doses around 200 mg/kg in rats and showe